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Oridonin

Oridonin

Catalog Number:
NP01367554APE
Mfr. No.:
APE-N1802
Price:
$196
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      • Overview

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          Background

          Oridonin has potent anti-tumor activity. Oridonin targets AE (AML1-ETO) oncoprotein. Exposure to oridonin induces apoptosis in AE-bearing leukemic cells through the activation of intrinsic apoptotic pathway and triggering a caspase-3-mediated degradation

      • Properties
        • Categories
          Anti-tumor reagent
          Alternative Name
          (1S,5S,6aS,9S,11bR)-1,5,6,14-tetrahydroxy-4,4-dimethyl-8-methylenedecahydro-1H-6,11b-(epoxymethano)-6a,9-methanocyclohepta[a]naphthalen-7(8H)-one
          CAS Number
          28957-04-2
          Molecular Formula
          C20H28O6
          Molecular Weight
          364.43
          Appearance
          A solid
          Purity
          99.51%
          Solubility
          insoluble in H2O; ≥13.6 mg/mL in DMSO; ≥4.9 mg/mL in EtOH
          Storage
          Store at -20°C
          SMILES
          [H][[email protected]@]12C(C)(C)CC[[email protected]](O)[[email protected]@]1(CO3)[[email protected]@]4([H])[[email protected]@]([[email protected]](O)[[email protected]](C5=C)CC4)(C5=O)[[email protected]@]3(O)[[email protected]]2O

          * For Research Use Only

    Documents

    COA (Certificate Of Analysis)

    HPLC (Retest)

    MSDS (Material Safety Data Sheet)

    Datasheet

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