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Overview
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Orfamide A is the major component of a family of cyclic lipopeptides produced by Pseudomonas fluorescens, reported in 2007. The orfamides were discovered by employing genomic analysis with an isotope-guided fractionation to identify metabolites produced by orphan gene clusters containing non-ribosomal peptide synthetases. Orfamide A has received scant investigation of its bioprofile but appears to be a selective antifungal agent. Uniquely, orfamide A lyses zoospores of the oomycete, Phytophthora ramorum, the cause of sudden oak death. Orfamide A has a profound effect on the swarming motility of bacteria on agar surfaces.
Orfamide A is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.Please contact us at for specific academic pricing.
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- Properties
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Overview
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