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Overview
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Calculated MW: 43kDa/47kDa/67kDa/134kDa/138kDa
Observed MW: 138kDaPlease contact us at for specific academic pricing.
Background
This gene encodes a Rho-GTPase-activating protein that promotes GTP hydrolysis of Rho subfamily members. Rho proteins are important mediators of intracellular signal transduction, which affects cell migration and cell morphogenesis. Mutations in this gene are responsible for OPHN1-related X-linked mental retardation with cerebellar hypoplasia and distinctive facial dysmorhphism.
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