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OPG Hi-5 Recombinant Protein

OPG Hi-5 Recombinant Protein

Catalog Number:
P001418282ABE
Mfr. No.:
Abe32-1642
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  • Size:
    10 µg
    Quantity:
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      • Overview

        • The Osteoprotegerin is fused to 17 amino acid His tag at C-terminus amd purified by proprietary chromatographic techniques. Osteoprotegerin acts as decoy receptor for rankl and thereby neutralizes its function in osteoclastogenesis. OPG inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local rankl/opg ratio. Osteoprotegerin may also play a role in preventing arterial calcification. May act as decoy receptor for trail and protect against apoptosis. Trail binding blocks the inhibition of osteoclastogenesis.

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      • Properties
        • Protein Name
          TNFRSF11B, OPG, OCIF, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TR1, MGC29565.
          Source
          Hi-5 cells
          Type
          Recombinant Proteins
          Purification
          Greater than 85.0% as determined by SDS-PAGE.
          Formulation
          Osteoprotegerin protein contains PBS pH-7.4 and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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