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OGG1 Recombinant Protein

OGG1 Recombinant Protein

Catalog Number:
P001416807ABE
Mfr. No.:
Abe32-2632
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  • Size:
    25 µg
    Quantity:
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      • Overview

        • OGG1 Recombinant Human produced in E. Coli is a single, non-glycosylated polypeptide chain containing 368 amino acids (1-345 a.a.) and having a molecular mass of 41.2 kDa. The OGG1 is fused to 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. OGG1 is a DNA glycosylase enzyme which takes part in base excision repair. OGG1 protein is the main enzyme accountable for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which arises as a result of exposure to reactive oxygen species (ROS). OGG1 shows beta lyase activity that nicks DNA 3'' to the lesion.

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      • Properties
        • Protein Name
          HMMH, HOGG1, MUTM, OGH1, AP lyase.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90.0% as determined by SDS-PAGE.
          Formulation
          0.5mg/ml solution containing 20mM Tris-HCl buffer pH-8, 0.1M NaCl and 40% Glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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