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Overview
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Specificity: Detects human CD3/CD20. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Odronextamab.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Isotype Control: Bulk Human IgG4 Isotype Control (IB4) [ICH2257]
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL methodPlease contact us at for specific academic pricing.
Background
ichorbio’s Odronextamab biosimilar is a hinge-stabilized, fully human IgG4-based CD3 x CD20 bispecific antibody (bsAb) that has demonstrated encouraging safety, tolerability and preliminary efficacy in a first-in-human study of patients with relapsed/refractory B-cell non-Hodgkin lymphoma.
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