Occludin / OCLN Antibody, 0.56 mg/ml

Occludin / OCLN Antibody, 0.56 mg/ml

Catalog Number:
A001547730IRE
Mfr. No.:
IR57-193s; IR57-193
Price:
$180
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      • Overview
        • Sensitivity: Endogenous
          Target name: OCLN / occludin
          Area: EMT / Junctional

          Please contact us at for specific academic pricing.

          Background

          This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]

      • Properties
        • Host
          Rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          Human, Mouse, Rat
          Clone
          pAb
          Immunogen
          Synthetic peptide / Intracellular domain corresponding to Human Occludin
          Storage
          Store at +4°C for short term storage. Long time storage is recommended at -20°C
          100mM Tris Glycine, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
          Molecular Weight
          52-68

          * For research use only.

      • Applications
        • Application
          WB; IF; IHC
        • Application Dilutions
          Western Blot 1:500–1:1000
          Immunofluorescence 1:200–1:400
          Immunohistochemistry (Frozen section) 1:100

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