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Overview
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NUDT4 produced in E. Coli is a single, non-glycosylated polypeptide chain containing 203 amino acids (1-180 a.a) and having a molecular mass of 22.7kDa. NUDT4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Nudix Type Motif 4 (NUDT4) regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates exemplifies a molecular switching activity with significant regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may be a factor in regulating intracellular trafficking.
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Overview