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NT1-20

NT1-20

Catalog Number:
P004516695LIF
Mfr. No.:
PEPTIDE-AS-010
Price:
$381
  • Size:
    1mg
    Quantity:
    Add to Cart:
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      • Overview

        • Blocks ASIC1a binding to RIPK1.
          NT1-20 is a tatylated membrane penetrating peptide derived from the N-terminus of the acid sensing ion channel 1a (ASIC1a), which can block ASIC1a binding receptor interacting protein kinase 1 (RIPK1) to its C terminus. ASIC1a ?mediates necroptosis via recruiting RIPK1, independent of its ion-conducting function, and though this mechanism NT1-20 can protect neurons against acidosis induced necroptosis in vitro. NT1-20 can also reduce neuronal damage in mouse models of ischemic stroke.

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          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Cell Penetrating Peptides
          Alternative Name
          Peptide NT1-20
          Molecular Formula
          C150H265N55O47S2
          Molecular Weight
          3655.22
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble in water
          Other Properties
          Sequence: H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Met-Glu-Leu-Lys-Thr-Glu-Glu-Glu-Glu-Val-Gly-Gly-Val-Gln-Pro-Val-Ser-Ile-Gln-Ala-OH,GRKKRRQRRRCMELKTEEEEVGGVQPVSIQA
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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