Nt-proCNP ELISA

C–type natriuretic peptide (CNP) is a paracrine growth factor widely expressed in tissues, including the vascular endothelium, where it is considered to provide vasoprotective functions. In endothelial cells and macrophages it is secreted in response to several stimuli, including inflammatory mediators. CNP also plays a critical role in linear growth.
CNP is rapidly degraded in tissues and negligible quantities enter the circulation. However, the N-terminal portion of the prohormone is not degraded at the source and circulates in significantly higher concentrations than CNP. Therefore Nt-proCNP is typically measured instead of CNP because of its increased stability and longer half-life.
Research areas include:

bone metabolism
non-septic systemic inflammatory response syndrome (SIRS)
cardiovascular disease
renal function

This kit number 04-BI-20812 replaces kit 04-BI-20872.

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