NR2C2 Polyclonal Antibody

NR2C2 Polyclonal Antibody

Catalog Number:
A001514162RED
Mfr. No.:
RD89748A
Price:
$416
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      • Overview
        • Calculated MW: 68kDa
          Observed MW: 71kDa

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          Background

          This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human NR2C2
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          NR2C2, TAK1, TR4 (Gene ID:7182; UniProt:P49116)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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