Name: NPS-2143 hydrochloride
Price: 196.00 USD

- Overview
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    Background
    
    NPS-2143 is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.NPS-2143 is useful for treatment of osteoporosis;
- Properties
  - Categories
    
    Calcium ion-sensing receptor antagonist
    
    Alternative Name
    
    NPS2143 hydrochloride;NPS 2143 hydrochloride; 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile;hydrochloride
    
    CAS Number
    
    324523-20-8
    
    Molecular Formula
    
    C24H26Cl2N2O2
    
    Molecular Weight
    
    445.38
    
    Purity
    
    98.00%
    
    Solubility
    
    ≥44.5 mg/mL in DMSO; insoluble in H2O; ≥11.43 mg/mL in EtOH with gentle warming and ultrasonic
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CC(C)(CC1=CC2=CC=CC=C2C=C1)NCC(COC3=C(C(=CC=C3)Cl)C#N)O.Cl
    
    * For Research Use Only