Name: NPHP1 Polyclonal Antibody (1.32 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: BC009789
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Fusion protein of human NPHP1
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1.32 mg/mL
  
  Antigen
  
  JBTS4, Juvenile nephronophthisis 1 protein, Nephrocystin 1, nephronophthisis 1 (juvenile), Nephronophthisis, NPH1, NPHP1, SLSN1 (UniProt:O15259)
  
  * For reference only.

Applications

Application

IHC; ELISA

Application	Dilutions
IHC	1:50-1:300
ELISA	1:5000-1:10000

NPHP1 Polyclonal Antibody (1.32 mg/mL) for IHC, ELISA

NPHP1 Polyclonal Antibody (1.32 mg/mL) for IHC, ELISA

Background

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