NLRP10 Polyclonal Antibody

NLRP10 Polyclonal Antibody

Catalog Number:
A001513276RED
Mfr. No.:
RD88428A
Price:
$416
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      • Overview
        • Calculated MW: 15kDa/18kDa/26kDa/34kDa/38kDa
          Observed MW: 39kDa

          Please contact us at for specific academic pricing.

          Background

          Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human NLRP10
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          NLRP10, CLR11.1, NALP10, NOD8, PAN5, PYNOD (Gene ID:338322; UniProt:Q86W26)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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