Nivolumab Biosimilar - Research Grade, Low Endotoxin

Nivolumab Biosimilar - Research Grade, Low Endotoxin

Catalog Number:
A001437359ICH
Mfr. No.:
ICH4009
Price:
$560
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      • Overview
        • Specificity: Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Nivolumab.
          Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
          Isotype Control: Bulk Human IgG4 Isotype Control (IB4) [ICH2257]
          Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method

          Please contact us at for specific academic pricing.

          Background

          Nivolumab biosimilar is a human monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. Nivolumab is an IgG4 kappa immunoglobulin that has a calculated molecular mass of 146 kDa. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line.

      • Properties
        • Host
          humanized
          Isotype
          IgG4 kappa
          Reactivity
          human
          Purification
          >95% by SDS-PAGE and HPLC
          Formulation
          Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
          Storage
          Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          1.0 - 5.0 mg/ml

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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