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Overview
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Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. NH2-PEG-NH2 is a homobibifunctional PEG derivative. It has a linear bifunctional PEG crosslinker with active primary amine or NH2 groups, which can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances. NH2-PEG-NH2 can be dissolved in conventional aqueous solutions and most organic solvents, and can also inhibit the non-specific binding of charged molecules to the modified surface.
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