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Overview
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Calculated MW: 17kDa/21kDa/22kDa/25kDa/32kDa/37kDa
Observed MW: 25-80KDaPlease contact us at for specific academic pricing.
Background
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
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