MYH7 Polyclonal Antibody

MYH7 Polyclonal Antibody

Catalog Number:
A001511413RED
Mfr. No.:
RD86870A
Price:
$416
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      • Overview
        • Calculated MW: 10kDa
          Observed MW: 11KDa

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          Background

          Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human MYH7
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% proclin300,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          MYH7, CMD1S, CMH1, MPD1, MYHCB, SPMD, SPMM, myosin-7, MYH7 (Gene ID:4625; UniProt:P12883)

          * For reference only.

      • Applications
        • Application
          WB; IF
        • Application Dilutions
          WB 1:500-1:2000
          IF 1:50-1:200

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