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Mubritinib (TAK 165)

Mubritinib (TAK 165)

Catalog Number:

L002370075APE

Mfr. No.:

APE-B1543

Price:

$145

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- Overview
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    Background
    
    Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk.
- Properties
  - Alternative Name
    
    4-[[4-[4-(triazol-1-yl)butyl]phenoxy]methyl]-2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3-oxazole
    
    CAS Number
    
    366017-09-6
    
    Molecular Formula
    
    C25H23F3N4O2
    
    Molecular Weight
    
    468.47
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in H2O; ≥76.9 mg/mL in DMSO with gentle warming; ≥3.09 mg/mL in EtOH with gentle warming and ultrasonic
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    C1=CC(=CC=C1CCCCN2C=CN=N2)OCC3=COC(=N3)C=CC4=CC=C(C=C4)C(F)(F)F
    
    * For Research Use Only

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