MSH4 Polyclonal Antibody (1 mg/mL) for WB

MSH4 Polyclonal Antibody (1 mg/mL) for WB

Catalog Number:
A001512004RED
Mfr. No.:
RD86885A
Price:
$416
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      • Overview
        • Calculated MW: 39kDa/117kDa
          Observed MW: 117kDa

          Please contact us at for specific academic pricing.

          Background

          This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          mouse; rat
          Immunogen
          Recombinant fusion protein of human MSH4
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          MSH4 (Gene ID:4438; UniProt:O15457)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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