MRPS18B Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

MRPS18B Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001508206RED
Mfr. No.:
RD252720A
Price:
$253
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      • Overview
        • Calculated MW: 29 kDa
          Observed MW: Refer to figures
          Gene Accession: BC005373

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          Background

          Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Fusion protein of human MRPS18B
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.6 mg/mL
          Antigen
          28S ribosomal protein S18-2, 28S ribosomal protein S18b, 28S ribosomal protein S18b, mitochondrial, C6orf14, DKFZp564H0223, HSPC 183, HSPC183, mitochondrial, Mitochondrial ribosomal protein S18 2, Mitochondrial ribosomal protein S18B, MRP S18 2, MRP S18 b, MRP S18b, MRP-S18-2, MRP-S18-b, MRPS 18B, MRPS18 2, Mrps18-b, MRPS18B, PTD017, RT18B, S18amt, S18mt-b (UniProt:Q9Y676)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:40-1:200
          ELISA 1:5000-1:10000

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