Name: MRPL40 Polyclonal Antibody (0.78 mg/mL) for IHC, ELISA
Price: 253.00 USD

Overview
- Gene Accession: BC009707
  
  Please contact us at for specific academic pricing.
  
  Background
  
  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.MRPL40 (Mitochondrial Ribosomal Protein L40) is a Protein Coding gene. Diseases associated with MRPL40 include Mrpl40-Related Disorder and Velocardiofacial Syndrome. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. GO annotations related to this gene include poly(A) RNA binding.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Fusion protein of human MRPL40
  
  Purification
  
  Antigen affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  0.78 mg/mL
  
  Antigen
  
  39S ribosomal protein L40, 39S ribosomal protein L40 mitochondrial, 39S ribosomal protein L40, mitochondrial precursor, FLJ41774, L40mt, MGC9400, mitochondrial, Mitochondrial ribosomal protein L40, MRP 40, MRP L22, MRP-L40, MRP40, MRPL22, MRPL40, NLVCF, Nuclear localization signal containing protein deleted in velocardiofacial syndrome, Nuclear localization signal deleted in velocardiofacial syndrome, Nuclear localization signal-containing protein deleted in velocardiofacial syndrome, RM40, Up-regulated in metastasis, URIM (UniProt:Q9NQ50)
  
  * For reference only.

Applications

Application

IHC; ELISA

Application	Dilutions
IHC	1:50-1:200
ELISA	1:5000-1:10000

MRPL40 Polyclonal Antibody (0.78 mg/mL) for IHC, ELISA

MRPL40 Polyclonal Antibody (0.78 mg/mL) for IHC, ELISA

Background

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