MPI Recombinant Protein

MPI Recombinant Protein

Catalog Number:
P001416747ABE
Mfr. No.:
Abe32-2562
Price:
  • Size:
    25 µg
    Quantity:
    Add to Cart:
      • Overview
        • MPI Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 382 amino acids (1-362) and having a molecular mass of 41.9 kDa. The MPI is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. MPI is a member of the mannose-6-phosphate isomerase type 1 family. Although MPI is expressed in all tissues, it can be found more abundantly in heart, brain and skeletal muscle. Localized to the cytoplasm, MPI exploits zinc as a cofactor and catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate. Mutations in the MPI gene are the cause of carbohydrate-deficient glycoprotein syndrome, type Ib.

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      • Properties
        • Protein Name
          Mannose-6-phosphate isomerase, PMI1, CDG1B, Phosphohexomutase, Phosphomannose isomerase, EC 5.3.1.8, FLJ39201.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90% as determined by SDS-PAGE.
          Formulation
          The MPI solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 5% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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