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Overview
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Mouse tPA Genetically Deficient Lung is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Flash-frozen immediately upon removal.
• Product Details
Species: Mouse
Antigen: tPA
Format: Frozen tissue
Storage Conditions: -70 C
• Mouse Model Details
Strain: C57BL6/SJL
Chromosome: 8
Gene: PLAT
Genomic Target: Exon 4
Mutation: 16 base pair deletion
Phenotype: Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA.Please contact us at for specific academic pricing.
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Overview