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Overview
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Mouse serum amyloid P (SAP) is a major acute phase protein that circulates as a ~230 kDa glycoprotein. It is composed of 10 identical subunits arranged as two cyclic pentameric discs and contains ~10% carbohydrate. Basal levels of SAP may vary significantly in different inbred mouse strains but SAP is a major acute phase protein in all strains. During acute chemical, physical, or inflammatory stimulus, its concentration can increase 50-100 fold within 24-48 hours. Changes can readily be detected in 4-6 hours. Measurement of the concentration of SAP is indicative of the extent and severity of an inflammatory stimulus and can be used to assess various modalities of treatment. The Mouse Serum Amyloid P ELISA (Mouse SAP ELISA) is a highly sensitive two-site enzyme linked immunoassay (ELISA) for measuring SAP in serum and plasma of mice.
The Mouse Serum Amyloid P ELISA (Mouse SAP ELISA) is for Research Use Only.Please contact us at for specific academic pricing.
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Overview