Name: Mouse NOGGIN Recombinant Protein (Animal Free) Lyophilized
Price: 613.00 USD

- Overview
  - Mouse NOGGIN Recombinant Protein (Animal Free) Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in with a purity of ? 98% by SDS-PAGE gel and HPLC analyses.
    
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    Background
    
    Noggin belongs to a group of diffusible proteins that bind to ligands of the TGF-? family, and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 anTagonist whose action was critical for proper formation of the head and other dorsal structures. Consequently, noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of noggin in mice results in prenatal death, and a recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant Murine Noggin is a 46.4 kDa disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains.
- Properties
  - Protein Name
    
    Nog
    
    Source
    
    E. coli
    
    Type
    
    Animal Free Proteins
    
    Purification
    
    >98% by SDS-PAGE gel and HPLC analyses.
    
    Storage
    
    The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    
    * These products are supplied for manufacturing, research and laboratory use only.

Mouse NOGGIN Recombinant Protein (Animal Free) Lyophilized

Mouse NOGGIN Recombinant Protein (Animal Free) Lyophilized

Background

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