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Mouse Interleukin-12

Mouse Interleukin-12

Catalog Number:
P001413219ABE
Mfr. No.:
Abe32-12174
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      • Overview

        • Heterodimer, p35: 21.7 kDa, p40: 35.8 kDa, total: 57.5 kDa kDa (p35: 193 aa, p40: 313 aa, total: 506 aa amino acids aa). Interleukin 12 (IL-12) is an inducer of cell-mediated immunity and is produced by dendritic cells, macrophages, and B cells after antigen stimulation. IL-12 functions to promote naïve T cell differentiation into the type 1 T helper cell (Th1) lineage. IL-12 also stimulates the production of interferon gamma (IFN-gamma ) and tumor necrosis factor alpha (TNF-alpha) from T cells and natural killer cells. Mouse IL-12 is active on human and mouse cells.

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      • Properties
        • Protein Name
          Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, NKSF, CLMF
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          P43432/P43431
          Gene ID
          16160

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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