Mouse Flt-3 Ligand

Mouse Flt-3 Ligand

Catalog Number:
P001413166ABE
Mfr. No.:
Abe32-12074
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      • Overview
        • Predicted MW: Monomer, 18.6 kDa (163 aa). Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7,) or in combination of IL-7 and interleukin 3 (IL-3).

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      • Properties
        • Protein Name
          SL cytokine, Flt3L, Fms-related tyrosine kinase 3 ligand
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
          Activity
          Biological Activity was determined by OCI-AML5 cell proliferation at = 1.0 x 10^5 units/mg. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

          More Information

          UniProt
          Gene ID
          14256

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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