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Overview
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Complement component C5a is a multifunctional proinflammatory mediator produced by complement cascade activation and causes inflammatory responses and cytokine production in septic shock, allergy, trauma, ischemic heart disease, pain, neurodegenerative diseases, and several other autoimmune diseases. C5a is rapidly cleaved to the C5a-DesArg form by the endogenous serum carboxypeptidase enzyme.
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- Properties
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Overview