Name: Mouse Beta-Nerve Growth Factor
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- Overview
  - Predicted MW: Dimer, 13.6/27.2 kDa (121/242 aa). Nerve growth factor beta (beta -NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. beta -NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. beta -NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat beta -NGF proteins are cross-reactive.
    
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- Properties
  - Protein Name
    
    NGF, Ngfb
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by TF-1 cell proliferation at <=5 ng/mL; >= 2.0 x 10^5 units/mL. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.
    
    More Information
    
    UniProt
    
    Q6LDU8
    
    Gene ID
    
    18049
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Mouse Beta-Nerve Growth Factor

Mouse Beta-Nerve Growth Factor

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