Mouse anti-KIF7 Monoclonal Antibody

Mouse anti-KIF7 Monoclonal Antibody

Catalog Number:
A001078740RED
Mfr. No.:
RD85484A
Price:
$253
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      • Overview
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          Background

          This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic Peptide
          Purification
          Protein A purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.4
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/mL
          Antigen
          EQYK340; kif7; KIF7; kinesin family member 7; kinesin like protein KIF7; Kinesin-like protein kif7; UNQ340 (Gene ID:374654; UniProt:Q2M1P5)

          * For research use only.

      • Applications
        • Application
          IHC (paraffin); IF

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