Mouse anti-BAX Monoclonal Antibody (1mg/mL) for WB, IHC (paraffin)

Mouse anti-BAX Monoclonal Antibody (1mg/mL) for WB, IHC (paraffin)

Catalog Number:
A001078694RED
Mfr. No.:
RD85549A
Price:
$253
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      • Overview
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          Background

          Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthetic Peptide of Bax
          Purification
          Protein A purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
          Storage
          Store at -20°C. Avoid repeated freeze / thaw cycles.
          Concentration
          1mg/mL
          Antigen
          Apoptosis regulator BAX; BAX; Bax-protein; BAX; BAXA; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; Bcl-2-like protein 4; BCL2 associated X protein; BCL2 associated X protein omega; BCL2 associated X protein transcript variant delta2; Bcl2-L-4; BCL2L4; membrane isoform alpha (Gene ID:581; UniProt:Q07812)

          * For research use only.

      • Applications
        • Application
          WB; IHC (paraffin)

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