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MMP 14 (MT1-MMP) prodomain, catalytic domain, His-tagged

MMP 14 (MT1-MMP) prodomain, catalytic domain, His-tagged

Catalog Number:

P001373806BIO

Mfr. No.:

30100112; 30100113

Price:

$729

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- Overview
  - Recombinant MT1-MMP prodomain-catalytic domain is produced as a periplasmic protein in E. coli. Investigation of MT1-MMP; Generation of MT1-MMP catalytic domain; Progelatinase A activation; inhibitor screening; antigen standard.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    More than 90% of total protein
    
    Formulation
    
    Recombinant MT1-MMP prodomain-catalytic domain is solubilized in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl₂.
    
    Storage
    
    Recombinant MT1-MMP prodomain-catalytic domain is stable until the expiry date given on the label if stored at -70 °C. It can be kept at -20 °C for several weeks. Repeated freezing and thawing should be avoided.
    
    Molecular Weight
    
    30.9 kDa
    
    * For Research Use Only
- Applications
  - Application Description
    
    The recombinant pro-MT1-MMP deletion mutant allows investigation of mechanisms of MT1-MMP activation. The MT1-MMP catalytic domain obtained upon activation is used to study the degradation of extracellular matrix proteins and the conversion of progelatinase A (matrix metalloproteinase 2) to active gelatinase A. MT1-MMP allows screening of matrix metalloproteinase inhibitors.

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