Name: MMAE
Price: 332.00 USD

- Overview
  - MMAE is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclonal antibody (MAB) which directs it to the cancer cells. Monomethyl auristatin E or MMAE is 100-1000 times more potent than doxorubicin. It is a very potent antimitotic agent that inhibits cell division by blocking the polymerization of tubulin.
    
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- Properties
  - Alternative Name
    
    Monomethyl auristatin E | 474645-27-7 | MMAE | MMAE (Monomethyl auristatin E) | V7I58RC5EJ | SGD-1010 | (2S)-N-[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-
    
    CAS Number
    
    474645-27-7
    
    Molecular Formula
    
    C39H67N5O7
    
    Molecular Weight
    
    717.98
    
    Purity
    
    95%
    
    Other Properties
    
    Melt Point (°C): >90°C (dec.)
    
    Storage
    
    Store at -20°C
    
    Shipping
    
    Dry ice
    
    SMILES
    
    CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC
    
    InChi
    
    InChI=1S/C39H67N5O7/c1-13-25(6)34(43(10)39(49)33(24(4)5)42-38(48)32(40-9)23(2)3)30(50-11)22-31(45)44-21-17-20-29(44)36(51-12)26(7)37(47)41-27(8)35(46)28-18-15-14-16-19-28/h14-16,18-19,23-27,29-30,32-36,40,46H,13,17,20-22H2,1-12H3,(H,41,47)(H,42,48)/t25-,26+,27+,29-,30+,32-,33-,34-,35+,36+/m0/s1
    
    InChi Key
    
    DASWEROEPLKSEI-UIJRFTGLSA-N
    
    PubChem CID
    
    11542188
    
    Others
    
    IUPAC Name: (2S)-N-[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamide
    
    Hazard Information
    
    Signal: Danger
    Hazard Statements: H315,H319,H335,H341,H302,H300,H330,H372,H360,H370
    Precautionary Statements: P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P260,P284,P281,P271,P270,P304+P340,P403+P233,P362+P364,P330,P320,P203,P264+P265,P301+P316,P301+P317,P318,P337+P317,P308+P316,P332+P317,P316,P319
    
    * For research use only. Not for use in human or animal.

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