MKK6(Phospho-Ser207) Antibody

MKK6(Phospho-Ser207) Antibody

Catalog Number:
A001548166RED
Mfr. No.:
RDSA62144
Price:
$483
  • Size:
    100μL
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Peptide sequence around phosphorylation site of serine 207 (V-D-S(p)-V-A) derived from Human MKK6.
          Purification
          Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
          Conjugate
          Unconjugated
          Formulation
          Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
          Storage
          Store at -20°C. Avoid freeze / thaw cycles.
          Concentration
          1.0 mg/mL
          Molecular Weight
          37kDa (Calculated)
          Antigen
          MAP kinase kinase 6;MAP2K6;MAPK/ERK kinase 6;MAPKK 6;MEK6 (Gene ID:5608; UniProt:P52564)

          * This product is for Research Use Only.

      • Applications
        • Application
          WB; IHC; IF
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:100-1:300
          IF 1:50-1:200

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