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MK-4827 tosylate

MK-4827 tosylate

Catalog Number:
L002369845APE
Mfr. No.:
APE-B1164
Price:
$246
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      • Overview

        • Please contact us at for specific academic pricing.

          Background

          MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.

      • Properties
        • Alternative Name
          (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carbimidic acid compound with 4-methylbenzenesulfonic acid (1:1)
          CAS Number
          1038915-73-9
          Molecular Formula
          C26H28N4O4S
          Molecular Weight
          492.59
          Appearance
          A crystalline solid
          Purity
          98.00%
          Solubility
          Soluble in DMSO
          Storage
          Store at -20°C
          SMILES
          N=C(O)C1=CC=CC(C1=N2)=CN2C3=CC=C([C@]4([H])CCCNC4)C=C3.CC5=CC=C(S(O)(=O)=O)C=C5

          * For Research Use Only

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