MGAT2 Recombinant Protein

MGAT2 Recombinant Protein

Catalog Number:
P001416727ABE
Mfr. No.:
Abe32-2537
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • MGAT2 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 439 amino acids (30-447a.a) and having a molecular mass of 50kDa. MGAT2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a golgi enzyme catalyzing an vital step in the conversion of oligomannose to complex N-glycans. MGAT2 enzyme has the characteristic glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. MGAT2 gene mutations may lead to carbohydrate-deficient glycoprotein syndrome, type II.

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      • Properties
        • Protein Name
          Mannosyl (Alpha-1, 6-)-Glycoprotein Beta-1, 2-N-Acetylglucosaminyltransferase, GlcNAc-T II, Mannoside Acetylglucosaminyltransferase 2, GNT-II, Beta-1, 2-N-Acetylglucosaminyltransferase II, N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltran
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85.0% as determined by SDS-PAGE.
          Formulation
          MGAT2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M urea.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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