Methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide) | (5,000:20,000 Da) LA:GA 50:50

Methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide) | (5,000:20,000 Da) LA:GA 50:50

Catalog Number:
PG01436222AKI
Mfr. No.:
AKI-AK037
Price:
$407
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      • Overview
        • Block copolymers synthesized so as to contain both biodegradable blocks and hydrophilic blocks. Can be used for a wide range of purposes.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Block Copolymers
          Alternative Name
          Methoxy Poly(ethylene glycol)-b-Poly(lactic-co-glycolic acid); mPEG-PLGA
          Other Properties
          (Mw ~5,000:20,000 Da) LA:GA 50:50

          * For Research Use Only

      • Applications
        • Application
          Forming "stealth" pegylated microparticles
      • Reference
        • 2023
          Mejía, Susana P., Richard da Costa Marques, Katharina Landfester, Jahir Orozco, and Volker Mailänder. . "Effect of Protein Corona on The Specificity and Efficacy of Nanobioconjugates to Treat Intracellular Infections".Macromolecular Bioscience(2023): 2300197.
          Product Usage: Decorated Nanoparticle Shell
          Ngai, Jessica W. "Delineating the Interaction between Liposomes and the Tumour Microenvironment".PhD dissertation University of Toronto2023
          Product Usage: Nanoparticle Shell
          Wu, Junhua, Meiling Jin, Quangdon Tran, Minwoo Kim, Song I. Kim, Juhee Shin, Hyewon Park et al. . "Employing the sustained-release properties of poly (lactic-co-glycolic acid) nanoparticles to reveal a novel mechanism of sodium-hydrogen exchanger 1 in neuropathic pain".Translational Research(2023).
          Product Usage: Decorated Nanoparticle Shell

          2022
          Bovone, Giovanni, Lucien Cousin, Fabian Steiner, and Mark W. Tibbitt. "Solvent Controls Nanoparticle Size during Nanoprecipitation by Limiting Block Copolymer Assembly".Macromolecules(2022).
          Product Usage: Nanoparticle Shell
          Greene, Ashlee. "Engineering Formulations for the Treatment of Periodontal Disease".PhD dissertation University of Pittsburgh2022
          Product Usage: Microparticle
          Kim, Sung Eun, Sung Jae Choi, Kyeongsoon Park, Hak-Jun Kim, Gwan Gyu Song, and Jae Hyun Jung. "Intra-Articular Injection of Rebamipide-Loaded Nanoparticles Attenuate Disease Progression and Joint Destruction in Osteoarthritis Rat Model: A Pilot Study".Cartilage13, no. 1 (2022): 19476035211069250.
          Product Usage: Nanoparticle Shell
          Zhang, Bokai, Massimiliano Galluzzi, Guoqiao Zhou, and Haoyang Yu. "A study of macrophage mechanical properties and functional modulation based on the Young's modulus of PLGA-PEG fibers".Biomaterials Science(2023).
          Product Usage: Structural

          2021
          Dhrona, Suchi. "Development of PSMA Targeted Polymer Nanoparticles to Treat Prostate Cancer By Boron Neutron Capture Therapy Directed Against PSMA".PhD diss., UCSF2021
          Product Usage: Nanoparticle Shell
          Li, Peter Y., Frank Bearoff, Pu Zhu, Zhiyuan Fan, Yucheng Zhu, Mingyue Fan, Laura Cort, Taku Kambayashi, Elizabeth P. Blankenhorn, and Hao Cheng. "PEGylation enables subcutaneously administered nanoparticles to induce antigen-specific immune tolerance".Journal of Controlled Release2021
          Product Usage: Decorated Nanoparticle Shell
          Ni, Ling, and You-Xin Li. "Anti-Human Epidermal Growth Factor Receptor 2 Single-Chain Fv Fragment-Decorated DM1 Nanoparticles for Specific Targeting of Human Epidermal Growth Factor Receptor 2-Positive Breast Tumor Cells".Journal of Biomedical Nanotechnology17, no. 3 (2021): 447-455.
          Product Usage: Decorated Nanoparticle Shell

          2020
          Bassin, Ethan J., Abigail R. Buckley, Jon D. Piganelli, and Steven R. Little. "TRI microparticles prevent inflammatory arthritis in a collagen-induced arthritis model".PloS one15, no. 9 (2020): e0239396.
          Product Usage: Nanoparticle Shell
          Huang, Di, Feng Yue, Jiamin Qiu, Meng Deng, and Shihuan Kuang. "Polymeric nanoparticles functionalized with muscle-homing peptides for targeted delivery of phosphatase and tensin homolog inhibitor to skeletal muscle".Acta Biomaterialia2020
          Product Usage: Decorated Nanoparticle Shell
          Popel, Aleksander S., Niranjan B. Pandey, Esak Lee, Jordan J. Green, and Ron B. Shmueli. "Biomimetic Peptide and Biodegradable Delivery Platform For The Treatment of Angiogenesis-And Lymphangiogenesis-Dependent Diseases".U.S. Patent Application16/989,416, filed November 19, 2020
          Product Usage: Nanoparticle Shell
          Syed, Abdullah Muhammad, Presley MacMillan, Jessica Ngai, Stefan Wilhelm, Shrey Sindhwani, Benjamin R. Kingston, Jamie LY Wu et al. . "Liposome imaging in optically cleared tissues".Nano Letters20, no. 2 (2020): 1362-1369.
          Product Usage: Nanoparticle Shell
          Zhou, Yang. "Development of Bortezomib-Loaded Nanoparticles for Locoregional Treatment of Hepatocellular Carcinoma".PhD diss., Johns Hopkins University2020
          Product Usage: Nanoparticle Shell

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