mEBI3 Recombinant Protein

mEBI3 Recombinant Protein

Catalog Number:
P001413053ABE
Mfr. No.:
Abe32-1129
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • EBI3 Mouse Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids and having a molecular mass of 22.9kDa. The Murine EBI3 is purified by proprietary chromatographic techniques. EBI3 has an induced expression in B lymphocytes in reaction to Epstein-Barr virus infection. EBI3 encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form iIL-27. EBI3 drives rapid clonal expansion of naive cd4(+) t-cells. EBI3 strongly synergizes with IL-12 to activate IFN-gamma production of naive cd4(+) t-cells. EBI3 mediates its biologic effects through the cytokine receptor wsx-1/tccr.

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      • Properties
        • Protein Name
          IL-27B, IL27B, IL 27-B, EBI-3, Interleukin-27 beta, IL-27 subunit beta, Epstein-Barr virus-induced gene 3 protein homolog, EBI3.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
          Formulation
          EBI3 was lyophilized from 10mM Sodium Citrate pH-3.
          Storage
          Lyophilized EBI3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EBI3 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          It is recommended to reconstitute the lyophilized EBI3 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

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