MCM2 Mouse Monoclonal Antibody

MCM2 Mouse Monoclonal Antibody

Catalog Number:
A001451651ZEN
Mfr. No.:
Zen-222443
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      • Overview
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          Background

          The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human; mouse; rat; monkey
          Immunogen
          Purified recombinant fragment of human MCM2 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Ascitic fluid containing 0.03% sodium azide.
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 102 kDa;Observed MW: 125 kDa
          Antigen
          (Gene ID:4171; UniProt:P49736)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P; FC; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/100-1/200
          FC 1/50-1/100
          ELISA 1/10000

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