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Mc-Val-Cit-PABC-PNP

Mc-Val-Cit-PABC-PNP

Catalog Number:
FC01365209APE
Mfr. No.:
APE-B1003
Price:
$364
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      • Overview

        • Please contact us at for specific academic pricing.

          Background

          Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker.

      • Properties
        • Categories
          Cathepsin cleavable ADC peptide linker
          Alternative Name
          (Z)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S,Z)-1-hydroxy-1-(((S)-5-((hydroxy(imino)methyl)amino)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxopentan-2-yl)imino)-3-methylbutan-2-yl)hexanimidic acid
          CAS Number
          159857-81-5
          Molecular Formula
          C35H43N7O11
          Molecular Weight
          737.76
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          ≥36.9 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
          Storage
          Store at -20°C
          SMILES
          CC([[email protected]@](/N=C(O)/CCCCCN1C(C=CC1=O)=O)([H])/C(O)=N/[[email protected]@](C(NC2=CC=C(COC(OC3=CC=C(N(=O)=O)C=C3)=O)C=C2)=O)([H])CCCNC(O)=N)C

          * For Research Use Only

    Documents

    COA (Certificate Of Analysis)

    MSDS (Material Safety Data Sheet)

    Datasheet

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