MAPKAPK-2(Phospho-Thr334) Antibody

MAPKAPK-2(Phospho-Thr334) Antibody

Catalog Number:
A001551644RED
Mfr. No.:
RDSA62281
Price:
$483
  • Size:
    100μL
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          MAPKAPK-2 encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Peptide sequence around phosphorylation site of threonine 334 (P-Q-T(p)-P-L) derived from Human MAPKAPK-2.
          Purification
          Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
          Conjugate
          Unconjugated
          Formulation
          Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
          Storage
          Store at -20°C. Avoid freeze / thaw cycles.
          Concentration
          1.0 mg/mL
          Antigen
          MAP kinase-activated protein kinase 2;MAPK-activated protein kinase 2;MAPK2;MAPKAP kinase 2;MAPKAPK-2 (Gene ID:9261; UniProt:P49137)

          * This product is for Research Use Only.

      • Applications
        • Application
          WB; IHC; IF
        • Application Dilutions
          WB 1:500-1:1000
          IHC 1:50-1:100
          IF 1:100-1:200

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