Name: MAPK1/MAPK3 Polyclonal Antibody (1 mg/mL) for IF
Price: 347.00 USD

Overview
- Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene./The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Properties
- Host
  
  rabbit
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant Protein of human MAPK1/MAPK3
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3
  
  Storage
  
  Store at -20°C. Avoid freeze-thaw cycles.
  
  Concentration
  
  1 mg/mL
  
  Antigen
  
  ERK1, ERK2, ERK1/2 (Gene ID:5594/5595; UniProt:P28482,P27361)
  
  * For reference only.

Applications

Application

IF

Application	Dilutions
IF	1:100-1:200

MAPK1/MAPK3 Polyclonal Antibody (1 mg/mL) for IF

MAPK1/MAPK3 Polyclonal Antibody (1 mg/mL) for IF

Background

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