MAN2B1 Polyclonal Antibody

MAN2B1 Polyclonal Antibody

Catalog Number:
A001514419RED
Mfr. No.:
RD90041A
Price:
$416
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      • Overview
        • Calculated MW: 56kDa/57kDa
          Observed MW: 57kDa

          Please contact us at for specific academic pricing.

          Background

          This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          mouse
          Immunogen
          Recombinant fusion protein of human MAN2B1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          MAN2B1, LAMAN, MANB (Gene ID:4125; UniProt:O00754)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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