Name: LOX Recombinant Protein
Price: Inquiry

- Overview
  - LOX Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 272 amino acids (169-417a.a) andhaving a molecular mass of 31.4kDa. LOX is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Lysyl Oxidase also known as LOX is an extracellular copper enzyme which initiates the crosslinking ofcollagens and elastin. LOX catalyzesoxidative deamination of the epsilon-amino group in certain lysine andhydroxylysine residues of collagens and lysine residues of elastin. Adding upto crosslinking extracellular matrix proteins, LOX plays a part in tumorsuppression. Moreover, defects in LOX are the cause of autosomal recessivecutis laxa type I, CL type I. Two transcript variants encoding dissimilar isoformshave been found for LOX.
    
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- Properties
  - Protein Name
    
    Lysyl Oxidase, EC 1.4.3.13, Protein-lysine 6-oxidase, Lysyloxidase.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 85% as determined by SDS-PAGE.
    
    Formulation
    
    LOX protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

LOX Recombinant Protein

LOX Recombinant Protein

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