Login / Register
0

Lopinavir

Lopinavir

Catalog Number:
L002369405APE
Mfr. No.:
APE-A8204
Price:
$188
  • Size:
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • Please contact us at for specific academic pricing.

          Background

          Lopinavir (also known as ABT-378) is a highly potent inhibitor of human immunodeficiency virus (HIV) protease that potently inhibits wild-type and mutant HIV protease with inhibition constant Ki values ranging from 1.3 to 3.6 pM. Lopinavir, a ritonavir analog designed to have a diminished interaction with Val82 in HIV protease, maintains a high potency inhibiting Val82 mutant HIV selected by ritonavir with 50% effective concentration EC50 value lower than 0.06 μM. Although the antiviral activity of ritonavir is considerably attenuated by human serum, lopinavir is less affected by human serum proteins and is 10-fold greater in potency than ritonavir in the presence of human serum.

      • Properties
        • Alternative Name
          Lopinavir; (2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
          CAS Number
          192725-17-0
          Molecular Formula
          C37H48N4O5
          Molecular Weight
          628.81
          Appearance
          A solid
          Purity
          98.55%
          Solubility
          ≥31.45 mg/mL in DMSO; insoluble in H2O; ≥48.3 mg/mL in EtOH
          Storage
          Store at -20°C

          * For Research Use Only

    We Also Recommend

    Atazanavir

    Atazanavir

    $223

    AZD6244 (Selumetinib)

    AZD6244 (Selumetinib)

    $188

    Darunavir

    Darunavir

    $292

    Note: If you don't receive our verification email, do the following:

    • Products
    Amerigo Scientific
    Support
    Contact Us
    Copyright © Amerigo Scientific. All rights reserved.