Lentiviral human USB1 sgRNA gene knockout kit

Human USB1

Gene symbol: USB1
Synonyms: C16orf57 hUsb1 HVSL1 Mpn1 PN
Species: HUMAN
Gene ID: 79650
Summary: This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_024598