Lentiviral human UGT1A6 sgRNA gene knockout kit

Human UGT1A6

Gene symbol: UGT1A6
Synonyms: GNT1 HLUGP HLUGP1 hUG-BR1 UDPGT UDPGT1-6 UGT-1A UGT-1C UGT-1E UGT1 UGT1-01 UGT1-03 UGT1-05 UGT1.1 UGT1.3 UGT1.5 UGT1A UGT1A1 UGT1A3 UGT1A5 UGT1A6S UGT1C UGT1E UGT1F
Species: HUMAN
Gene ID: 54578
Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_001072