Lentiviral human SQSTM1 sgRNA gene knockout kit

Human SQSTM1

Gene symbol: SQSTM1
Synonyms: A170 DMRV FTDALS3 NADGP OSIL p60 p62 p62B PDB3 ZIP3
Species: HUMAN
Gene ID: 8878
Summary: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_003900:3:3