Lentiviral human RPTOR sgRNA gene knockout kit

Human RPTOR

Gene symbol: RPTOR
Synonyms: KOG1 Mip1
Species: HUMAN
Gene ID: 57521
Summary: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
NM numbers targeted (Accession number:Exon:CDS Fragment): NM_020761:8:8 NM_001163034:8:8